Ticlopidine induced colitis: a histopathological study including apoptosis

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Ticlopidine induced colitis: a histopathological study including apoptosis.

AIMS To describe ticlopidine related microscopic colitis and to assess the occurrence of apoptosis in the colon epithelium. METHODS A series of colorectal biopsy samples from nine patients with ticlopidine related chronic diarrhoea were analysed. Biopsies were also taken from five of these patients between two and four months after ticlopidine withdrawal. The number of apoptotic cells in the ...

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Interstitial pneumonia induced by ticlopidine.

A 67-year-old female non-smoker, who had been diagnosed with familial hypercholesterolemia associated with severe atherosclerosis of the coronary, carotid and vertebral arteries, developed interstitial pneumonia 4 months after initiating ticlopidine to inhibit platelet aggregation. The lymphocyte stimulation test by ticlopidine was positive and bronchoalveolar lavage fluid showed an increase in...

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Severe ticlopidine-induced cholestatic syndrome.

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1998

ISSN: 0021-9746

DOI: 10.1136/jcp.51.4.280